White paper

Considerations in monoclonal antibody production

Learn how monoclonal antibodies may be used to support the development of therapeutic products.

Research models and services Antibody production
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The utility of antibodies as reagents is of paramount importance in research, diagnosis and clinical development.

It is hard to imagine a world without monoclonal antibodies (mAbs). They are widely used in the scientific community and have assisted in the advancement of research and development.

As reagents and therapeutics in their own right, they have played an important role in the advancement of basic research, diagnostics and product development, and they have delivered huge patient benefits across a wide range of therapeutic areas.

Moreover, technologies such as antibody phage display and humanized mice have expanded the available options to generate novel mAbs, in particular human or humanized mAbs for therapeutic purposes.

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This is the third in a series of three white papers reviewing the custom antibody production and the use antibodies in the development of therapeutic products. In this white paper 'Considerations in the production of antibodies as reagents: Monoclonal antibodies'

 

  • Discover the key steps of optimal monoclonal antibody production
  • Gain insight into the scaling up production methodologies
  • The principal considerations in purification strategies to eliminate antibody aggregates

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