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Evaluating malignant pleural mesothelioma with Athymic Nude Mouse models

This article summarizes work published in the International Journal of Cancer and discusses how researchers evaluated antitumor activity in three patient-derived xenograft models.

They used Inotiv’s athymic nude mice to study the effectiveness of an oral bioavailable small molecule as a potential treatment option.

Along with the preliminary results, this case study also discusses the advantages of the Athymic Nude Mouse to support patient-derived xenografts (PDX).

Download this case study and explore:

  • Reproducing the biological and pharmacological features of a human tumor in the Athymic Nude Mouse

  • The benefits of creating a patient-derived xenograft with the Athymic Nude Mouse

  • How Inotiv can enable innovative research for rare disease studies

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